Upstate NY is a beautiful region in New York. Home to Hudson Valley, Saratoga Springs, Finger Lakes, and the Catskills, it is the perfect place for a relaxing nature getaway. In this article, we have handpicked the best boutique & luxury hotels in Upstate New York with top-notch comfort, design, and services. Hemlock Neversink is one of the best luxury boutique hotels in Sullivan County, Upstate NY. Nestled on 230 acres of beautiful grounds, the hotel is the perfect place in the Catskills for a wellness getaway. It offers 44 cozy guest rooms & suites across 5 buildings. Their design revolves around green and earthy shades, accented by handcrafted furniture, custom quilts, patterned carpets, and upscale amenities.